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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Genetic toxicity: in vitro

Currently viewing:

Administrative data

Endpoint:
genetic toxicity in vitro
Remarks:
Type of genotoxicity: other: QSAR estimate
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: this model was developed for regulatory assessment of chemical substances
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
2009

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: QSAR estimate
GLP compliance:
no
Remarks:
not applicable to QSAR models
Type of assay:
other: CAESAR QSAR model for Mutagenicity v.1.0.0.5

Test material

Constituent 1
Reference substance name:
SMILES
IUPAC Name:
SMILES

Results and discussion

Any other information on results incl. tables

Overview of QSAR/SAR estimations on mutagenicity potential of chloroethylene

Method

 

Results

Remarks

Reference

CAESAR

QSAR

model for

Mutagenicity

v.1.0.0.5

Activity: Mutagen

(refer Appendix 3 to this CSR)

Supportive data

CAESAR

QSAR model

for Mutagenicity

v.1.0.0.5

Applicant's summary and conclusion

Conclusions:
not mutagenic