Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 309-798-8 | CAS number: 101012-97-9
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
No data
Key value for chemical safety assessment
Additional information
The Substance is poorly soluble in water and long-term toxicity testing should be considered according to REACH Regulation, Section 9.1.3, Column 2. However, the Registrant will not perform a study on the long-term toxicity to fish, but adapt the information requirements as follows. The Registrant wants to emphasize that with regard to the available acute toxicity data for DTDA, aquatic invertebrates are more sensitive to the Substance than fish. Even if the short-term toxicity data might not give a true measure of the toxicity of this poorly water-soluble substance, the data still reflect the relative sensitivity of the organisms to the Substance. The 96-h LL50 for fish was determined to be > 100 mg/L, while the effect levels for aquatic invertebrates and algae were lower (aquatic invertebrates: 48-h EL50 = 46.9 mg/L; algae: 72-h ErL50 = 12.3 mg/L). Avoiding unnecessary testing of vertebrate animals is in line with the REACH Regulation 1907/2006, which states in §25 that testing on vertebrate animal shall be undertaken as a last resort. Therefore, the testing strategy aims at investigating the long-term toxicity on aquatic invertebrates in a first step. Depending on the outcome of this test, a long-term study on fish will be performed.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
