1-vinylimidazole

Acute Toxicity: other routes

Administrative data

Endpoint:

acute toxicity: other routes

Adequacy of study:

other information

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

study well documented, meets generally accepted scientific principles, acceptable for assessment

Data source

Reference

Reference 1

Reference Type:

study report

Title:

Unnamed

Report date:

1953

Reference 2

Reference Type:

study report

Title:

Unnamed

Report date:

1951

Materials and methods

Principles of method if other than guideline:

other: BASF-test

GLP compliance:

no

Test material

Test material information

Constituent 1

Reference substance name:

1-vinylimidazole

EC Number:

214-012-0

EC Name:

1-vinylimidazole

Cas Number:

1072-63-5

Molecular formula:

C5H6N2

IUPAC Name:

1-ethenyl-1H-imidazole

Details on test material:

IUCLID4 Test substance: as prescribed by 1.1 - 1.4

Test animals

Species:

mouse

Administration / exposure

Route of administration:

subcutaneous

Vehicle:

water

Doses:

0.25, 0.5, 1.0, 2.0 and 4.0 cm3/kg (ca. 260, 520, 1040, 2080 and 4160 mg/kg bw)

No. of animals per sex per dose:

1 (2080 and 4160 mg/kg bw)
5 (260, 520 and 1040 mg/kg bw)

Control animals:

no

Results and discussion

Effect levels

Sex:

not specified

Dose descriptor:

LD50

Effect level:

ca. 750 mg/kg bw

Based on:

test mat.