1-[bis[3-(dimethylamino)propyl]amino]propan-2-ol

Henry's Law constant

Link to relevant study record(s)

Reference

Endpoint:

Henry's law constant

Type of information:

calculation (if not (Q)SAR)

Adequacy of study:

supporting study

Study period:

2023

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

accepted calculation method

Principles of method if other than guideline:

The Henry´s Law Constant of the substance was calculated by using the computer program EUSES v2.2. This parameter is calculated from temperature corrected experimental vapour pressure and water solubility.

GLP compliance:

no

Key result

H:

0.005 Pa m³/mol

Temp.:

25 °C

H:

0.003 Pa m³/mol

Temp.:

12 °C

Remarks on result:

other: Henry's law constant calculated at environmental temperature

Conclusions:

A scientifically accepted calculation method is used to determine the Henry´s Law Constant with EUSES v2.2. No GLP criteria are applicable for the usage of this tool and the estimation is easily repeatable. The Henry's Law Constant of the substance was estimated to be 5.49E-03 Pa m³/mol at 25 °C and estimated from the ratio of the vapour pressure (1.7 Pa at 20°C) and the water solubility (100 g/L at 20°C).

Description of key information

A scientifically accepted calculation method is used to determine the Henry´s Law Constant. No GLP criteria are applicable for the usage of this tool and the estimation is easily repeatable. The Henry's Law Constant of the substance was estimated to be 5.49E-03 Pa m³/mol at 25°C.

Key value for chemical safety assessment

Henry's law constant (H) (in Pa m³/mol):

0.005

at the temperature of:

25 °C