Registration Dossier

Ecotoxicological information

Toxicity to microorganisms

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

NOEC = 41.1 mg/L (from ready biodegradation test, 55% biodegradation in toxicity control within 14 days)

Key value for chemical safety assessment

Additional information

No standard studies evaluating the effect of Glycerides, C12-18 di- and tri- (CAS No. 91744-28-4) on respiration inhibition of aquatic microorganisms are available. Therefore, a ready biodegradability study is used to derive a NOEC for this endpoint. If a compound degrades well in a ready biodegradability test, or does not inhibit the degradation of a positive control at a certain concentration, this concentration can be used as a NOEC value. This approach is in accordance with the Guidance on information requirements and chemical safety assessment (Chapter R.7b, ECHA 2012).

A substance can be assumed to be not inhibitory of the activity of aquatic microorganisms if, in the toxicity control of a ready biodegradation test, more than 25% biodegradation occurs within a period of 14 days (OECD Guideline 301). For Glycerides, 12-18, di- and tri- a biodegradation screening test according to OECD 301B is available (Flach, 2012, see section 5.2.1). This test includes a toxicity control containing 41.1 mg/L of test material. Within 14 days, 55% biodegradation took place in this toxicity control clearly indicating the lack of toxic potential of the test item to activated sludge microorganisms, and therefore, the test item concentration of 41.1 mg/L can be used as a NOEC.

Based on the above information it is considered that Glycerides, C12-C18 di and tri- is not inhibitory of aquatic microorganisms activity and further testing for this endpoint is not deemed necessary.