Registration Dossier
Registration Dossier
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EC number: 700-476-6 | CAS number: 119895-68-0
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Report date:
- 1992
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Deviations:
- yes
- Principles of method if other than guideline:
- The volume of the test solution was reduced from 3.0 1 to 1.5 1. The CO2 formed by biodegradation was absorbed with NaOH and determined on a carbon analyzer. Due to the poor solubility of the test substance in water, an emulsifier was used to achieve a better distribution in the medium. The test substance was added directly into the medium without preparing a stock solution.
- GLP compliance:
- yes
Test material
- Reference substance name:
- 2,2-difluoro-2H-1,3-benzodioxole-4-carbaldehyde
- EC Number:
- 700-476-6
- Cas Number:
- 119895-68-0
- Molecular formula:
- C8H4F2O3
- IUPAC Name:
- 2,2-difluoro-2H-1,3-benzodioxole-4-carbaldehyde
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge (adaptation not specified)
- Duration of test (contact time):
- 28 d
Initial test substance concentrationopen allclose all
- Initial conc.:
- 10.9 mg/L
- Based on:
- test mat.
- Initial conc.:
- 21.6 mg/L
- Based on:
- test mat.
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- CO2 evolution
Reference substance
- Reference substance:
- aniline
Results and discussion
% Degradationopen allclose all
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 1
- Sampling time:
- 28 d
- Remarks on result:
- other: test substance concentration 10.9 mg/l
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 0
- Sampling time:
- 28 d
- Remarks on result:
- other: test substance concentration 21.6 mg/l
BOD5 / COD results
- Results with reference substance:
- 87 % of the reference substance (Aniline) was degraded after 28 d
Applicant's summary and conclusion
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- The test substance is not readily biodegradable in the OECD301B test (CO2 Evolution Test).
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