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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

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Administrative data

Link to relevant study record(s)

Description of key information

The inhibition of the degradation activity of activated sludge is not anticipated when the test substance introduced in appropriate low concentrations

Key value for chemical safety assessment

Additional information

The toxicity of Na2EDTA on microorganisms was tested in an activated sludge respiration inhibition test according to OECD guideline 209 [Van Ginkel & Stroo, 2000], for justification for read-across see IUCLID 5, Chapter 13. The EC20 value after 30 min was measured to be > 500 mg/L. For Na4EDTA a similar low toxicity on activated sludge was measured in an respiration inhibition test according to ISO 8192 [BASF AG, 1988]. In this test a concentration of 1000 mg/L test substance caused no effect on the respiration rate of the bacteria.

Results of nitrification are available by Hu (2003). In a 24 h nitrification inhibition test the EC50 of H4EDTA to microorganism was determined to be 2.4 mM/L, equivalent to 700 mg/L.