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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Eye irritation

Currently viewing:

Administrative data

Endpoint:
eye irritation
Remarks:
other: read across
Type of information:
migrated information: read-across based on grouping of substances (category approach)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Referenceopen allclose all

Title:
No information
Author:
Anonymous
Year:
2011
Bibliographic source:
OECD Toolbox v2.0, November 2010
Title:
No information
Author:
Anonymous
Year:
2010
Bibliographic source:
Merck KGaA data sheet

Materials and methods

Test guideline
Guideline:
other: read across (grouping: skin irritation inclusion rules by BfR-ketones)
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Aluminium tris(2,4-pentanedionato-O,O')
EC Number:
237-741-6
EC Name:
Aluminium tris(2,4-pentanedionato-O,O')
Cas Number:
13963-57-0
Molecular formula:
C15H21AlO6
IUPAC Name:
aluminium tris(2,4-pentanedionato-O,O')

Results and discussion

In vivo

Results
Irritation parameter:
other: Modified maximum average score
Basis:
mean
Score:
30.4
Max. score:
110

Any other information on results incl. tables

See attached OECD Toolbox v2.0 study for eye irritation/corrosion.

Note that v3.1 gave identical results.

Applicant's summary and conclusion

Interpretation of results:
irritating
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
Classification Xi;R36 (DSD), respectively Eye irritant category 2 with H319