Registration Dossier
Registration Dossier
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EC number: 205-029-4 | CAS number: 131-56-6
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Repeated dose toxicity: via oral route - systemic effects
Link to relevant study records
- Endpoint:
- sub-chronic toxicity: oral
- Type of information:
- migrated information: read-across based on grouping of substances (category approach)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Guideline:
- other: read across (Ecosar class poly phenols, strict)
- GLP compliance:
- no
- Species:
- rat
- Sex:
- male/female
- Route of administration:
- oral: unspecified
- Duration of treatment / exposure:
- 90d
- Dose descriptor:
- NOAEL
- Effect level:
- 236 mg/kg bw/day (nominal)
- Based on:
- test mat.
- Sex:
- male/female
- Basis for effect level:
- other: 90d test, oral, rat; undefined organ, undefined (systemic) effect
- Critical effects observed:
- not specified
Reference
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed
- Dose descriptor:
- NOAEL
- 236 mg/kg bw/day
- Study duration:
- subchronic
- Species:
- rat
Repeated dose toxicity: inhalation - systemic effects
Endpoint conclusion
- Endpoint conclusion:
- no study available
Repeated dose toxicity: inhalation - local effects
Endpoint conclusion
- Endpoint conclusion:
- no study available
Repeated dose toxicity: dermal - systemic effects
Endpoint conclusion
- Endpoint conclusion:
- no study available
Repeated dose toxicity: dermal - local effects
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
The OECD Toolbox study for repeated dose (oral, rat, 90 d) gave as NOAEL result 236 mg/kg bw/day
Justification for classification or non-classification
The substance should not be classified for STOT RE.
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