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Administrative data

Endpoint:
genetic toxicity in vitro
Remarks:
Type of genotoxicity: other: chromosome damage, genotoxicity, mutagenicity
Type of information:
(Q)SAR
Adequacy of study:
key study
Study period:
2010
Reliability:
2 (reliable with restrictions)
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
2010
Report date:
2010

Materials and methods

Principles of method if other than guideline:
Software used: DEREK Nexus, version 2.0.0, 2010 LHASA Ltd, Leeds, UK
GLP compliance:
no
Type of assay:
other: QSAR using Derek Nexus, version 2.0.0

Test material

Constituent 1
Chemical structure
Reference substance name:
Ethyl 2-cyano-3-ethoxyacrylate
EC Number:
202-299-5
EC Name:
Ethyl 2-cyano-3-ethoxyacrylate
Cas Number:
94-05-3
Molecular formula:
C8H11NO3
IUPAC Name:
ethyl 2-cyano-3-ethoxyacrylate

Results and discussion

Test results
Species / strain:
not specified
Metabolic activation:
not specified
Genotoxicity:
other: no alert
Cytotoxicity / choice of top concentrations:
not specified

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information):
other: no alert

No alert for chromosome damage, genotoxicity and mutagenicity of the Ethyl- 2-cyano-3-ethoxyacrylate was detected by DEREK Nexus version 2.0.0.

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