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Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Description of key information

BCF have been calculated for various representative components of these streams. The calculated values range from 99 to 5790.

Key value for chemical safety assessment

Additional information

A measured BCF is not available for any streams in this category. As the log Kow of some category members is >3 the bioaccumulation endpoint cannot be waived. However, ECHA's Guidance on Information Requirements and Chemical Safety Assessment R7c Endpoint Specific Guidance (2008) indicates that before commissioning a new vertebrate test alternative sources of data on the bioaccumulation potential of a chemical should be used.

Nonpolar substances have been shown to have a linear relationship between log Kow and BCF in the log Kow range 1 to 6. Several QSAR have been developed that calculate the BCF of non-polar, hydrophobic compounds on the basis of their log Kow (e.g. Veith et al, 1979 and USEPA, 2008). The method of Veith et al (1979) was used to calculate the BCF for representative substances of the streams since most of the substances fall within the applicability domain of the model. For the substance with a log Kow >6, a parabolic method has been used for calculation. The calculated BCF of representative components of the streams range from 99 to 5790.