Registration Dossier
Registration Dossier
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EC number: 276-627-0 | CAS number: 72388-18-2
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- Please seee read-across justification documen in chapter 13
- Reason / purpose for cross-reference:
- read-across: supporting information
- Key result
- Duration:
- 3 h
- Dose descriptor:
- EC0
- Effect conc.:
- >= 1 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth inhibition
- Validity criteria fulfilled:
- yes
- Conclusions:
- According to data of the structurally-related 2-Octyldodecan-1-ol ithe substance 2-dodecylhexadean-1-ol is not toxic at concentrations >= 1000 mg/l to activated sludge of a municipal sewage treatment plant.
Reference
Description of key information
Experimental data on one representative of the category (C20) shows no toxicity to microorganisms up to the limit of solubility. These results were cross-read to 2-dodecylhexadecanol.
Key value for chemical safety assessment
Additional information
No data on toxicity on microorganisms are available for 2-dodecylhexadecanol but for the structurally related 2-octyldodecan-1-ol. Feibig (2009) reported reliable (Klimisch 2) results for a GLP compliant OECD 209 test with activated sludge using the structurally related 2-octyldodean-1-ol. 2-Octyldodecan-1-ol is not toxic at concentrations up to 1000 mg/l to activated sludge of a municipal sewage treatment plant, based on growth inhibition. Due to the structural similarity and based on its very low water solubility 2-dodecylhexadecanol is also considered to be not toxic to microorganisms.
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