Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
hydrolysis
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
other information
Study period:
2000
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2000
Report date:
2000

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
Estimation based on chemical structure.
GLP compliance:
no

Test material

Radiolabelling:
no

Study design

Analytical monitoring:
no

Results and discussion

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Executive summary:

ZK 91535 does not contain functional groups which are susceptible to hydrolytic cleavage. ZK 91535 is to be considered hydrolytically stable in the relevant pH region 4 - 9.

The test substance molecule and all of its functional groups belong to a class of substances that are generally resistant to hydrolysis, e.g.: alkanes, alkenes, alkynes, benzenes/biphenyls, polycyclic aromatic hydrocarbons, heterocyclic polycyclic aromatic hydrocarbons, halogenated aromatics, aromatic nitro compounds, aromatic amines, alcohols, phenols, glycols, ethers, aldehydes, ketones, carboxylic acids, sulfonic acids (Ref.: Lyman, W. J.; Reehl, W. F.; Rosenblatt, D. H.; Handbook of Chemical Property Estimation Methods, McGraw-Hill New York 1982, p. 7-4).