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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Description of key information

The 48h EC50 range for Toxicity to aquatic invertebrates ranged from 0.62 (DCPD 92% proprietary study) to 8 mg/l (MITI Japan) . With a short term NOEC range of < 1.8 (MITI Japan) to 0.22 mg/l (Safepharm Laboratories, 1995).  The MITI study identified in the SIDS Initial Assessment was unavailable for review.

Key value for chemical safety assessment

Additional information

Data was not available for 3a,4,5,6,7,7a-hexahydro-4,7 -methano-1H-indene, therefore available data has been read across from 3a,4,7,7a-tetrahydro-4,7 -methanonoindene.

Safepharm Laboratories (1995) provided the key study endpoint value. The study identified a 48h median effect concentration (EC50) of DCPD 92% to Daphnia magna. This was calculated to be 0.62 mg/l with 95% confidence limits of 0.52-0.72 mg/l. The no observed effect concentration was 0.22 mg/l. Only limited information was provided on the solvent vehicle and results are reported based on nominal concentrations. However, the study is considered suitable as a key study for this endpoint as it is the most conservative value reported.

The MITI study reviewed in the OECD SIDS was unavailable for review but showed an EC50 of 8 mg/l. As it has been through the regulatory review process previously it has been included here as a supporting study. Passino-Reader (1997) is a near guideline study which provides an EC50 of 4.2 mg/L for Daphnia pulex. The study is also considered adequate as a supporting study.