Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 293-209-3 | CAS number: 91052-49-2
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Readily biodegradable: 79.5% in 28 days (OECD 301B)
Key value for chemical safety assessment
Additional information
No experimental data evaluating the biodegradation potential of Glycerides, C12-18 mono- and di- (CAS No. 91052-49-2) are available. Therefore, biodegradation data from a structurally related category member, Glycerides, C12-18 di- and tri- (CAS No. 91744-28-4) are used as read-across in accordance with Regulation (EC) No. 1907/2006, Annex XI, 1.5. Both substances are esters formed from the combination of C12-18 fatty acids and glycerol. Due to differences on the degree of esterification of these substances (mono and diester for CAS No. 91052-49-2, and di and triester for CAS No. 91744-28-4), a higher biodegradation rate can be expected for the target substance. Generally, larger and branched molecules are considered as a worst-case approach, since the chain length and substitutions are determining factors for biodegradation of fatty acid alcohol esters (Bozcar et al., 2001; Dias and Alexander, 1971). As biodegradation will tend to increase at higher degree of esterification, reading across from Glycerides, C12-18 di- and tri- represents a worst-case scenario for the target substance and therefore it is justified.
A study evaluating the potential for ready biodegradability of Glycerides, C12-18 di- and tri- (CAS No. 91744-28-4) is available (Flach, 2012). The test was conducted according to OECD Guideline 301B, under GLP conditions. Activated sludge microorganisms were exposed to the test substance for a period of 28 days, and biodegradation followed by measuring the CO2 production in the test vessels. After 28 days, the test substance reached 79.5% biodegradation, and therefore, it can be considered as readily biodegradable. The results obtained in the toxicity control (55% biodegradation within 14 days) show that Glycerides, C12-18 di- and tri- is not toxic to and therefore non-inhibitory of activated sludge microorganisms activity.
Based on the results of the test performed on the structurally related analogue substance (in accordance with Regulation (EC) No. 1907/2006, Annex XI, 1.5), Glycerides, C12-18 mono- and di- (CAS No. 91052-49-2) can be regarded as readily biodegradable.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
