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Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
GLP compliance:
no
Type of method:
HPLC method
Partition coefficient type:
octanol-water
Analytical method:
high-performance liquid chromatography
Type:
log Pow
Partition coefficient:
3.5
Temp.:
30 °C
pH:
7.2
Conclusions:
The Partition Coefficient (n-octanol/water) of Coolact® 10 has been determined to be log POW 3.5.
Executive summary:

The aim of the study was to determine the log Pow of Coolact 10, following the OECD guideline n°117.

The Partition Coefficient (n-octanol/water) of Coolact® 10 has been determined to be log POW 3.5.

Description of key information

The log Pow of the substance was determined to be 3.5 at 30°C and pH 7.2

Key value for chemical safety assessment

Log Kow (Log Pow):
3.5
at the temperature of:
30 °C

Additional information

The octanol-water partiton coefficient of the substance was determined in accordance with the standardised guideline OECD 117. The study was awarded a reliability score of 1 in accordance with the criteria set forth by Klimisch et al. (1997).

Under the conditions of the study, the log Pow of the substance was determined to be 3.5 at 30°C and pH 7.2