Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 500-245-8 | CAS number: 70750-57-1
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
Endpoint specific guidance (ECHA, 2008) indicates that absorption of substances following exposure by inhalation, skin contact or ingestion may be predicted based on log Pow and water solubility. Experimentally determined results for Terpenes and terpenoids, turpentine-oil, alpha pinene fraction, oligomers are:
* Partition coefficient n-octanol/water (log value): >4.04
* Water solubility: <0.322 mg/L.
ECHA (2008) indicates that uptake of substances by the lung and by the gastrointestinal tract is favoured by moderate log P values (between -1 and 4) with micellular solubilisation favoured where log P is >4 and water solubility is low (< 1 mg/l). Data summarised above indicate that the log Pow for this substance exceeds 4 and water solubility is low suggesting that some uptake after exposure via these routes may occur although the extent of uptake is unclear.
For dermal absorption to occur, a substance must be sufficiently soluble in water to partition from the stratum corneum into the epidermis with low uptake if the water solubility is below 1 mg/l (ECHA 2008). Log P values between 1 and 4 favour dermal absorption, while a log P >4 limits the rate of transfer between the stratum corneum and the epidermis limiting skin penetration. Phys-chem data summarised above suggests that Terpenes and terpenoids, turpentine-oil, alpha pinene fraction, oligomers should not be readily absorbed by skin.
No experimental data are available to characterise the toxicokinetic behaviour of this substance.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
