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EC number: 203-581-0 | CAS number: 108-42-9
Endpoint summary
Administrative data
Description of key information
Additional information
Based on weight of evidence approach no. of studies were reviewed for bioaccumulation from reliable sources having Klimish rating 2 and 4 for CAS No.:108-42-9
The summary of the results are presented below:
Sr. No |
Endpoint name |
Value |
Interpretation of result |
Conclusion |
Sources |
1. |
BCF |
0.8 – 2.2 L/kg |
Non bioaccumulative |
Bioconcentration factor (24-336 hr exposure) for carp exposed to 14.7 and 0.67 µg l-1 under continuous flow-through conditions, 0.8 and 2.2, respectively. Whole-body excretion rate constant 0.21 hr-1.This low value of BCF of 3-chloroaniline indicates its non bioaccumulative nature as the BCF factor is less than the bio-concentration threshold of 2000. |
Experimental data for CAS : 108-42-9 |
2. |
BCF |
11.5 |
Non bioaccumulative |
The Bioconcentration factor (BCF) for zebrafish exposed to 3-chloroaniline (0.0002 mg/L) under static conditions was reported as 11.5 suggesting that 3-chloroaniline is non bioaccumulative in nature as the BCF factor is less than the bio-concentration threshold of 2000. |
Experimental data for CAS : 108-42-9 |
3. |
BCF |
8.1 |
Non bioaccumulative |
The estimated bioconcentration factor (BCF) for 3-Chloroaniline is 8.1,which does not exceeds the bioconcentration threshold of 2000.Thus, it is concluded that 3-Chloroaniline is not expected to bioaccumulate in the food chain because it does not exceed the BCF criteria. |
Predicted data for CAS : 108-42-9 |
4. |
BCF |
8.08 |
Non bioaccumulative |
The estimated bioconcentration factor (BCF) for 3-Chloroaniline is 8.08,which does not exceeds the bioconcentration threshold of 2000.Thus, it is concluded that 3-Chloroaniline is not expected to bioaccumulate in the food chain because it does not exceed the BCF criteria. |
Predicted data for CAS : 108-42-9 |
Based on the studies summarized in the above table for target substance 3-Chloroaniline,the bioconcentration value (BCF) was found to vary between 0.8 to 11.5. This low value of BCF of 3-Chloroaniline indicates its non bioaccumulative nature as the BCF factor is less than the bio-concentration threshold of 2000.
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