potassium 4-iodo-2-sulfonato-benzoic acid

Particle size distribution (Granulometry)

Administrative data

Endpoint:

particle size distribution (granulometry)

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Study performed according to OECD 110

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2008

Report date:

2008

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions)

GLP compliance:

yes (incl. QA statement)

Type of distribution:

counted distribution

Test material

Test material information

Constituent 1

Reference substance name:

-

EC Number:

426-620-5

EC Name:

-

Cas Number:

619297-89-1

Molecular formula:

C7H4IO5S.K

IUPAC Name:

potassium 2-carboxy-5-iodobenzene-1-sulfonate

Details on test material:

- Name of test material : 4-lodo-2-potassiumsulfonato-benzoicacid
- Physical state: solid
- Purity test date: 99.1 % w/w
- Lot/batch No.: ENCK000509
- Expiration date of the lot/batch: October 02, 2010

Results and discussion

Particle size

Particle size 1

Percentile:

D50

Remarks on result:

other: Migrated from fields under 'Mass median diameter' as D50 percentile. No source field for Standard deviation.

Particle size 2

Percentile:

D10

Mean:

2

Particle size 3

Percentile:

D50

Mean:

8.1

Particle size 4

Percentile:

D90

Mean:

31.5

Any other information on results incl. tables

The particle size distribution of the 1st test series is shown in figure 1 (page 9) and of the 2nd test series in figure 2 (page 10). For each test series fractions (left axis of the ordinate) and the sittings (right axis of the ordinate) are presented in volume % as a function of the particle size. The median particle size L50 (50 % of particle volume with lower particle diameter) deduced from these distributions are: 1st test series: L50 = 8.139 µrn 2nd test series: L50 = 8.148 µrn The average of the median particle size L50 was 8.1 µrn. The particle size L10 (10 % of particle volume with lower particle diameter) deduced from these distributions are: 1st test series: L10 = 1.948 2nd test series: L10 = 1.972 um The average of the particle size Lto was 2.0 µm. The particle size L90 (90 % of particle volume with lower particle diameter) deduced from these distributions are: 1st test series: L90 = 31.404 µm 2nd test series: L90 = 31.692 µm The average of the particle size L90 is Lgo = 31.5 µm

Applicant's summary and conclusion

Conclusions:

The median particle size for ICBSK is 8.1 µm

Executive summary:

The following values were deduced from the particle size distribution of 4-lodo-2- potassiumsulfonato-benzoic acid (AE F141158): Particle size Remark L10 2.0 µrn L50 8.1 µm Median particle size L90 31.5 µm