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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
hydrolysis
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2009
Report date:
2009

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: Annex to EEC Directive 92/69/EEC, Method C7, OECD Guidelines for Testing of Chemicals, Method 111.
GLP compliance:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent

Study design

Buffers:
Buffer solutions were typically prepared as follows:
pH 4.0: Potassium dihydrogen orthophosphate (3.0 g) and disodium hydrogen orthophosphate dodecahydrate (6.4 g) were dissolved in purified water (950 ml) and the pH was adjusted to 4.0 ± 0.05 with orthophosphoric acid. The volume was then adjusted to 1000 ml with purified water.
pH 7.0: Potassium dihydrogen orthophosphate (13.6 g) was dissolved in purified water (1900 ml) and 1M sodium hydroxide (60 ml) was added. The pH was confirmed to be 7.0 ± 0.05. The volume was then adjusted to 2000 ml with purified water.
pH 9.0: Disodium tetraborate decahydrate (16.6 g) and potassium dihydrogen orthophosate (1.8 g) were dissolved in purified water (950 ml) and the pH was adjusted to 9.0 ± 0.05 with 1M hydrochloric acid. The volume was then adjusted to 1000 ml with purified water.

Results and discussion

Preliminary study:
The preliminary study showed that at pH 4 and pH 7 and 50 ± 0.5ºC, less than 10% hydrolysis had occurred after 120 hours (5 days), equivalent to a half-life of greater than 1 year under environmental conditions (25°C). No further testing was therefore necessary at these pH values.

Applicant's summary and conclusion

Conclusions:
M3MC-Carboxylate was determined to be hydrolytically stable under acidic and neutral conditions, but hydrolysed under basic conditions.
Executive summary:

M3MC-Carboxylate was determined to be hydrolytically stable under acidic and neutral conditions, but hydrolysed under basic conditions.