Registration Dossier
Registration Dossier
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EC number: 201-199-9 | CAS number: 79-36-7
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- other: No GLP and no guideline was followed. The number of animals was low and few data on methodology was provided.
Cross-reference
- Reason / purpose for cross-reference:
- reference to other study
Data source
Reference
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 1 951
Materials and methods
- Principles of method if other than guideline:
- 2000ppm vapor inhalation by rats.
- GLP compliance:
- not specified
- Test type:
- other: inhalation of known vapour concentration
- Limit test:
- no
Test material
- Reference substance name:
- Dichloroacetyl chloride
- EC Number:
- 201-199-9
- EC Name:
- Dichloroacetyl chloride
- Cas Number:
- 79-36-7
- Molecular formula:
- C2HCl3O
- IUPAC Name:
- 2,2-dichloroacetyl chloride
- Details on test material:
- - Name of test material (as cited in study report): Dichloroacetyl chloride.
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- inhalation
- Type of inhalation exposure:
- not specified
- Vehicle:
- other: no data
- Details on inhalation exposure:
- 2000ppm during 4 hours, observation was during 14 days
- Analytical verification of test atmosphere concentrations:
- not specified
- Duration of exposure:
- 4 h
- Concentrations:
- 2000 ppm
- No. of animals per sex per dose:
- total 6 animals
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LC50
- Effect level:
- 2 000 ppm
- Exp. duration:
- 4 h
- Mortality:
- Observation of mortality during 14 days
Any other information on results incl. tables
Two of 6 animals were died. |
Applicant's summary and conclusion
- Conclusions:
- LC50 is >2000ppm/4hours (rat)
- Executive summary:
LC50 is >2000-ppm/4hours (rat)
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