Registration Dossier

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

EC50 (48 h) = 64.4 mg/L (mean measured concentration) for Daphnia magna (OECD 202)

Key value for chemical safety assessment

Additional information

The acute toxicity of Glycerides, palm-oil mono-, hydrogenated, acetates (CAS No. 93572-32-8) to aquatic invertebrates was investigated in a study by Sloman (2012). The test was conducted according to OECD 202, under GLP conditions under a static water regime. Daphnia magna was exposed to the test substance for 48 h at 21 ± 1°C. Analytical monitoring of the test concentrations was performed. Measured concentrations (3.66, 8.11, 18.6, 40.9 and 82.7 mg/L) are in some cases above the water solubility value estimated for this substance (1.3-7.4 mg/L). The substance is a complex UVCB and therefore, two representative components were chosen to monitor concentrations in the test solutions. These components were probably the most water soluble. 

After the exposure period, immobilization was observed in all treatment groups being 20, 30, 35, 35 and 60% at 3.66, 8.11, 18.6, 40.9 and 82.7 mg/L (mean measured concentrations). Precipitated test substance was observed at all test concentrations (cloudy to very cloudy solutions) and particulate material was attached to some of the daphnids. In the range finding study conducted with this substance, nominal concentrations of 0.012 to 120 mg/L (nominal) were applied. All solutions were clear and colourless with no precipitate, except for the highest concentrations (12 and 120 mg/L), which were reported to have slightly to very cloudy test solutions. In the range-finding test immobilization was observed only at the highest concentrations. The above information indicates that the observed effects in the definitive study could be caused by physical interference with precipitated test material, rather than to toxicity. Nevertheless, since toxicity cannot be excluded completely, the reported EC50 (48 h) of 64.4 mg/L (mean measured concentration) is considered for further assessment.