Reaction mass of 2-{[2-(2-hydroxyethoxy)ethoxy]carbonyl}benzoic acid and 2,2'-oxydiethanol

Vapour pressure

Link to relevant study record(s)

Reference

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2012

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

guideline study with acceptable restrictions

Reason / purpose for cross-reference:

reference to same study

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.4 (Vapour Pressure)

Deviations:

no

Principles of method if other than guideline:

The Knudsen effusion apparatus used in this work was recently developed, representing the state-of-the-art. Its quality is regularly tested through the study of reference substances.
For the experiments, the effusion cells are loaded with approx. 500 mg of compound to be studied. The mass loss in each experiment is determined by careful weighing, in an analytical balance Mettler Toledo AT201 with a resolution of 0.01 mg. A more detailed description of the apparatus and of the experimental procedure can be found in the literature (Fonseca et al. Chem. Thermodyn. 43 (2011) 1942-1949 ).
The quality of the apparatus was verified through the thorough study of reference compounds and the comparison of the obtained results with the values existing in literature, at temperatures ranging from -4 °C to 140 °C and pressures varying from 0.001 Pa to 1 Pa.
Phenanthrene, anthracene, benzoic acid and benzanthrone were used as reference compounds. For all these substances, the agreement between the measured vapor pressures and the literature data is remarkable, confirming the superior quality of the apparatus used.

GLP compliance:

yes

Type of method:

effusion method: by loss of weight or by trapping vaporisate

Temp.:

20 °C

Vapour pressure:

0.207 Pa

Temp.:

25 °C

Vapour pressure:

0.343 Pa

Temp.:

50 °C

Vapour pressure:

3.393 Pa

Conclusions:

Based on the results, the vapor pressure of the compound is calculated as being equal to 0.21 Pa (2.1 x 10-3 mbar) at 20 °C, and 0.34 Pa (3.4 x 10-3 mbar) at 25 °C (Fonseca, 2012).

Executive summary:

The vapor pressure of a sample of Additive 1132 (Ester PSA + DEG) was measured using the Knudsen effusion method (mass-loss technique), according to the guidelines OECD 104 / EU A.4. Based on the results, the vapor pressure of the compound is calculated as being equal to 0.21 Pa (2.1 x 10^-3 mbar) at 20 °C, and 0.34 Pa (3.4 x 10^-3 mbar) at 25 °C.

Description of key information

Based on the results of an OECD Guideline test (No. 104), the vapor pressure of the compound is calculated as being equal to 0.21 Pa (2.1 x 10-3 mbar) at 20 °C, and 0.34 Pa (3.4 x 10-3 mbar) at 25 °C.

Key value for chemical safety assessment

Vapour pressure:

0.21 Pa

at the temperature of:

20 °C