Registration Dossier
Registration Dossier
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EC number: 214-269-9 | CAS number: 1118-84-9
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation / corrosion
- Remarks:
- other: estimated
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- other: Authoritative data base
- Title:
- Danish QSAR study for CAS No.: 1118-84-9
- Author:
- Danish EPA Model
- Year:
- 2 012
- Bibliographic source:
- QSAR predictions by Danish Environmental Protection Agency (EPA)model powered by OASIS database:-DK-EPA
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other:
- Principles of method if other than guideline:
- Skin irritation (Severe vs mild). Multicase model.
- GLP compliance:
- no
Test material
- Reference substance name:
- Allyl acetoacetate
- EC Number:
- 214-269-9
- EC Name:
- Allyl acetoacetate
- Cas Number:
- 1118-84-9
- Molecular formula:
- C7H10O3
- IUPAC Name:
- allyl acetoacetate
- Reference substance name:
- 118-84-9
- IUPAC Name:
- 118-84-9
- Details on test material:
- - Name of test material: allyl acetoacetate
- Molecular formula: C7H10O3
- Molecular weight: 142.15
- Substance type: Organic
Constituent 1
Constituent 2
Test animals
- Species:
- other: No data
- Strain:
- not specified
Test system
- Type of coverage:
- not specified
- Preparation of test site:
- not specified
- Vehicle:
- not specified
- Controls:
- not specified
Results and discussion
In vivo
Results
- Irritation parameter:
- overall irritation score
- Basis:
- mean
- Reversibility:
- no data
- Remarks on result:
- other: Non-irritating
- Irritant / corrosive response data:
- Negative
Applicant's summary and conclusion
- Conclusions:
- Allyl acetoacetate is estimated o be non-irritating to skin.
- Executive summary:
Allyl acetoacetate is estimated o be non-irritating to skin.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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