Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 214-269-9 | CAS number: 1118-84-9
Dermal absorption
Administrative data
- Endpoint:
- dermal absorption
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- other: Authoritative data base
- Title:
- Danish QSAR study for CAS No.: 1118-84-9
- Author:
- Danish EPA Model
- Year:
- 2 012
- Bibliographic source:
- QSAR predictions by Danish Environmental Protection Agency (EPA)model powered by OASIS database; EPI Suite (DERMWIN) Various versions of EPI Suite dating back from 1990-2004. Equation 6 (modified
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other:
- Principles of method if other than guideline:
- Data is from DEPA QSAR database
- GLP compliance:
- no
Test material
- Reference substance name:
- Allyl acetoacetate
- EC Number:
- 214-269-9
- EC Name:
- Allyl acetoacetate
- Cas Number:
- 1118-84-9
- Molecular formula:
- C7H10O3
- IUPAC Name:
- allyl acetoacetate
- Details on test material:
- - Name of test material: allyl acetoacetate
- Molecular formula: C7H10O3
- Molecular weight: 142.16
- Substance type: Organic
Constituent 1
- Radiolabelling:
- not specified
Test animals
- Species:
- other: no data
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Type of coverage:
- not specified
- Vehicle:
- not specified
Results and discussion
Percutaneous absorption
- Remarks on result:
- other: Dermal absorption: 0.02200 mg/cm2/event (MODERATE)
Applicant's summary and conclusion
- Conclusions:
- Dermal absorption value of allyl acetoacetate is estimated to be 0.02200mg/cm2/event (Moderate).
- Executive summary:
Dermal absorption value of allyl acetoacetate is estimated to be 0.02200mg/cm2/event (Moderate).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
