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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Description of key information

Based on the weight of evidence appraoch, the no observed effect concentration (NOEC) value of allyl acetoacetate in algae Pseudokirchneriella subcapitata in a 72 hr studybased upon effect on growthwas estimated to be 166.1863 mg/L. In addition, the effective concentration (EC50) value of allyl acetoacetate in green algae Chlorococcales in a 24 hr study based upon effect on physiology was estimated to be 1217.818 mg/L. The other studies also indicate that the chemical shall not exhibit aquatic toxicity to aquatic algae.

Key value for chemical safety assessment

EC50 for freshwater algae:
1 217.818 mg/L
EC10 or NOEC for freshwater algae:
166.186 mg/L

Additional information

The no observed effect concentration (NOEC) value of allyl acetoacetate in algae Pseudokirchneriella subcapitata in a 72 hr studybased upon effect on growthwas estimated to be 166.1863 mg/L. Thus, considering the CLP Criteria for aquatic classification of the substance , it is concluded that allyl acetoacetateshall not exhibit short term toxicity to Pseudokirchneriella subcapitata.

The various weight of evidencestudies can be summarised as follows :

Sr. No

End point name

Value

Unit

Species

Basis for effect

1

NOEC 

166.1863

mg/l

Pseudokirchnerella subcapitata

Growth

2

EC50

166.8663

mg/l

Pseudokirchnerella subcapitata

Growth

3

EC50

1217.818

 

mg/l

Chlorococcales

Physiology

4

EC50

298.786

mg/l

Green algae

No data

5

EC50

403.7247

mg/l

Selenastrum capricotum

Growth rate

6

EC50

>978.0

mg/l

Selenastrum capriconutum

Growth rate