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Environmental fate & pathways

Adsorption / desorption

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In accordance with Regulation 1907/2006 (EC) Annex XI adsorption/desorption study was not conducted as the study is technically not feasible. Based on the experiments and analysis of the test item performed and due to an analytical method detection limit equal to 0.050 mg/L it is concluded that a reliable method is not available in the 0.010 mg/L range for the test item as required in the 106 OECD guideline. In addition, the 106 OECD guideline indicates that the Adsorption/Desorption study must be performed at one half water solubility. It was determined from a reported water solubility value of less than 0.040 mg/L that the Adsorption/Desorption study would have to be conducted at 0.020 mg/L, which is below the analytical detection limit of 0.050 mg/L. Therefore, an Adsorption/Desorption study following OECD Guideline 106 would not be applicable for the test item. Based on the analytical methodology presented and the results demonstrating a water solubility at less than 0.040 mg/L, a waiver for the Adsorption/Desorption study is appropriate to fulfill regulatory requirements. 

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