Registration Dossier

Administrative data

Key value for chemical safety assessment

Effects on fertility

Description of key information

In accordance with REACH Annex XI, section 2, testing is technically not feasible as a consequence of the properties of the substance (hydrolytically unstable substance and quasi-instantaneously degraded in contact with moist skin or mucuous membranes to form Vanadium pentoxide and hydrogen chloride). There are sufficient data on the cleavage products (Vanadium pentoxide and hydrogen chloride were already registered in the frame of REACH) and the breakdown substance are exempted to Registration following Annex V (Entry I).

Link to relevant study records
Reference
Endpoint:
screening for reproductive / developmental toxicity
Data waiving:
study technically not feasible
Justification for data waiving:
other:
Reproductive effects observed:
not specified
Effect on fertility: via oral route
Endpoint conclusion:
no study available
Effect on fertility: via inhalation route
Endpoint conclusion:
no study available
Effect on fertility: via dermal route
Endpoint conclusion:
no study available

Effects on developmental toxicity

Description of key information

In accordance with REACH Annex XI, section 2, testing is technically not feasible as a consequence of the properties of the substance (hydrolytically unstable substance and quasi-instantaneously degraded in contact with moist skin or mucuous membranes to form Vanadium pentoxide and hydrogen chloride). There are sufficient data on the cleavage products (Vanadium pentoxide and hydrogen chloride were already registered in the frame of REACH) and the breakdown substance are exempted to Registration following Annex V (Entry I).

Link to relevant study records
Reference
Endpoint:
developmental toxicity
Data waiving:
study technically not feasible
Justification for data waiving:
other:
Abnormalities:
not specified
Developmental effects observed:
not specified
Effect on developmental toxicity: via inhalation route
Endpoint conclusion:
no study available
Effect on developmental toxicity: via dermal route
Endpoint conclusion:
no study available

Justification for classification or non-classification

Vanadium trichloride oxide quasi-instantaneously degraded in contact with moist skin or mucuous membranes to form Vanadium pentoxide and hydrogen chloride.

Testing Vanadium trichloride oxide for carcinogenicity is for this reason not relevant at all, but breakdown products have to be considered (classification for Vanadium pentoxide and hydrogen chloride have been elaborated in the frame of REACH).

For these reasons, no classification could be set for toxicity to reproduction.