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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Biodegradation in water: screening tests

Administrative data

Endpoint:
biodegradation in water: ready biodegradability
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
other: Prediction model
Title:
Bio-degradation in water by Environmental Science Center’s PBT profiler
Author:
Environmental Science Center
Year:
2010
Bibliographic source:
PBT profiler, Office of Chemical Safety and Pollution Prevention , U.S. Environmental Protection Agency; version 1.301

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: Modelling database
Principles of method if other than guideline:
PBT profiler database
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
2,2,2-trifluoroacetamide
EC Number:
206-559-9
EC Name:
2,2,2-trifluoroacetamide
Cas Number:
354-38-1
Molecular formula:
C2H2F3NO
IUPAC Name:
2,2,2-trifluoroacetamide
Test material form:
solid: crystalline
Details on test material:
- Name of test material : 2,2,2-trifluoroacetamide
- Molecular formula : C2H2F3NO
- Substance type: Organic
- Physical state: Solid

Study design

Oxygen conditions:
other: modelling database
Inoculum or test system:
not specified
Duration of test (contact time):
38 d

Results and discussion

% Degradation
Parameter:
other: Halflife
Value:
50
Sampling time:
38 d
Details on results:
Half life = 38 days

Any other information on results incl. tables

Media

Half life

(days)

Percent in Medium

Water

38

34%

Applicant's summary and conclusion

Interpretation of results:
readily biodegradable
Conclusions:
2,2,2-trifluoroacetamide was estimated to be 50% biodegradable in water in 38 days (half-life) indicating that 2,2,2-trifluoroacetamide is readily biodegradable in water since the half life is less than the threshold of 60 days (to qualify the chemical as persistent)
Executive summary:

Based on level III fugacity model 2,2,2-trifluoroacetamide was estimated to be 50% biodegradable in water in 38 days (half-life) indicating that 2,2,2-trifluoroacetamide is readily biodegradable in water since the half life is less than the threshold of 60 days (to qualify the chemical as persistent)