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Ecotoxicological information

Toxicity to birds

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Description of key information

The chemical safety assessment according to Annex I of Regulation (EC) No. 1907/2006 does not indicate the need to investigate further the toxicity to birds.

Key value for chemical safety assessment

Additional information

According to chapter R.7c “Endpoint specific guidance” of the “Guidance on information requirements and chemical safety assessment” published by ECHA (2012) testing for avian toxicity may not be required if a risk for secondary poisoning is negligible (e.g. if the substance is readily biodegradable, has a low potential for bioaccumulation and moreover there is no evidence of toxicity in mammalian repeat dose or reproduction tests). Regarding the results from mammalian studies of the test substance ethane-1,2-diyl palmitate (CAS 624 -03 -3) there is no evidence of any toxic effects neither in the repeated dose testing nor in the testing on reproduction. In addition no adverse effects were observed in the aquatic tests. Furthermore, the test substance is readily biodegradable and the potential for bioaccumulation is assumed to be low (see expert statement on bioaccumulation Section 5.3). Thus, the substance has a negligible risk for secondary poisoning and there is no need to investigate further the effects on birds.