Registration Dossier

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: guideline-conform study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1975
Report Date:
1975

Materials and methods

Test guideline
Qualifier:
equivalent or similar to
Guideline:
other: Probit-analysis (Linder/Weber)
Deviations:
no
GLP compliance:
no
Test type:
acute toxic class method

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test animals

Species:
rat
Strain:
Wistar
Sex:
female

Administration / exposure

Route of administration:
oral: gavage
Vehicle:
other: sesam oil
Doses:
6
No. of animals per sex per dose:
10

Results and discussion

Effect levels
Sex:
female
Dose descriptor:
LD50
Effect level:
518 mg/kg bw
Based on:
test mat.

Any other information on results incl. tables

dose [mg/kg]              mortality

200                            0/10

320                            0/10

400                            2/10

500                            7/10

800                            8/10

1250                          10/10

Applicant's summary and conclusion

Interpretation of results:
harmful
Remarks:
Migrated information