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Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

In the literature a patch test and a photopatch test with 5% butyl flufenamate ointmentin in human patients are described.

Flufenaminsäurebutylester (butyl flufenamate) was negative in both publications.


Migrated from Short description of key information:
No internal sensitization studies were conducted with Flufenaminsäurebutylester:
Results of sensitization studies with Flufenaminsäurebutylester were found in the literature (May 2011):

Patch test (human) butyl flufenamate 5% ointment: negative
(Kubo, Y. et al. (1986); Contact Dermatitis v. 15, p. 109-111)

Photopatch test (human) butyl flufenamate 5% ointment: negative
(Kurumaji, Y. et al. (1991); Contact Dermatitis v. 25, p. 218-223)

Justification for classification or non-classification

Based on the study results a classification according to Directive 67/548/EEC and Regulation (EC) No. 1272/2008 (CLP) is not required.

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