Registration Dossier
Registration Dossier
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EC number: 606-191-2 | CAS number: 18979-61-8
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
- Migrated from Short description of key information:
The skin sensitising potential of 4-butylbenzene-1,3-diol was assessed in the Sens-It-Iv programme.
The effect of the substance on IL-18 CD86 expression in MUTZ-3 and THP-1 cells was found to be negative. It can be concluded that the substance is not sensitising.
The effect of the substance on IL-18 production in NCTC cells was found to be negative. It can be concluded that the substance is not sensitising.
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
