Registration Dossier
Registration Dossier
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EC number: 295-714-4 | CAS number: 92128-22-8
Endpoint summary
Administrative data
Description of key information
The substance is corrosive to the skin and highly irritating to the eyes.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (corrosive)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Skin irritation
In a dermal irritation test the test substance was corrosive to the skin of rabbits according to OECD TG 404. Within the 14-day post observation period no restitution with normal skin findings at the application site were observed (Suberg, 1984).
Eye irritation
In an eye irritation test the test substance was highly irritating to the eyes of rabbits according to OECD TG 405. Within the 21-day post-observation period restitution with normal eye findings were observed (Suberg, 1984).
Justification for selection of skin irritation / corrosion endpoint:
Only one key study available
Justification for selection of eye irritation endpoint:
Only one key study available
Effects on skin irritation/corrosion: corrosive
Effects on eye irritation: highly irritating
Justification for classification or non-classification
Skin irritation
Not classified under Annex I of Directive 67/548/EEC or Annex VI-1 of Regulation (EC) No 1272/2008. Differing from this the irreversible damage to the skin of rabbits leads to the following classification according to Annex I of Regulation (EC) No 1272/2008: Category 1C (H314: Causes severe skin burns and eye damage).
Eye irritation
Not classified under Annex I of Directive 67/548/EEC or Annex VI-1 of Regulation (EC) No 1272/2008.
According to the Guidance on Application of Regulation (EC) No. 1272/2008, chapter 3.3, if a substance is classified as Skin Corrosive Category 1 then serious damage to eyes is implicit and there is no need to proceed with classification for eye effects.Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
