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Ecotoxicological information

Toxicity to terrestrial arthropods

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Reference
Endpoint:
toxicity to bees: acute contact
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
key study
Justification for type of information:
For details and justification of read-across please refer to the read-across report attached to IUCLID section 13.
Reason / purpose for cross-reference:
read-across source
Key result
Duration:
48 h
Dose descriptor:
LD50
Effect conc.:
> 100.4 µg per animal
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality
Validity criteria fulfilled:
yes
Conclusions:
The contact LD50 value of SY-83 (L-(+)-lactic acid) in the honey bee was determined to be greater than 100.4 µg/bee, the highest concentration tested.
Executive summary:

Mortality rates in all five treatment groups were similar to those observed in the control and solvent control groups. Mortalities did not appear to be treatment related. In conclusion, SY-83 was classified as relatively non-toxic to honey bees. The 48 hour contact LD50 value for SY-83 to honey bees was greater than 100.4 µg/bee, the highest dosage tested.

This information is used in a read-across approach in the assessment of the target substance. For details and justification of read-across please refer to the read-across report attached to IUCLID section 13.

Description of key information

The contact LD50 value of lactic acid in the honey bee was determined to be greater than 100.4 µg/bee, the highest concentration tested.

Key value for chemical safety assessment

Additional information