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Environmental fate & pathways

Adsorption / desorption

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Endpoint:
adsorption / desorption: screening
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
supporting study
Justification for type of information:
For details and justification of read-across please refer to the read-across report attached to IUCLID section 13.
Reason / purpose for cross-reference:
read-across source
Type:
Koc
Value:
< 20.9 dimensionless
Type:
log Koc
Value:
< 1.32 dimensionless
Details on results (HPLC method):
Lactic acid eluted before phenol; phenol has a designated log Koc of 1.32. No relevant differences in the results were observed at neutral pH and pH 2.0.
Validity criteria fulfilled:
yes
Conclusions:
Lactic acid log Koc < 1.32.
Executive summary:

The adsorption coefficient (Koc) of lactic acid 93 % aq. on soil and on sewage sludge was determined using high performance liquid chromatography (HPLC). The Koc and log Koc value of the test substance at neutral pH and at pH 2 was < 20.9 and < 1.32, respectively.

This information is used in a read-across approach in the assessment of the target substance. For details and justification of read-across please refer to the read-across report attached to IUCLID section 13.

Endpoint:
adsorption / desorption, other
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
key study
Justification for type of information:
For details and justification of read-across please refer to the read-across report attached to IUCLID section 13.
Reason / purpose for cross-reference:
read-across source
Type:
Koc
Value:
1 L/kg
Remarks on result:
other: Estimate from Molecular Connectivity Index
Type:
Koc
Value:
0.222 L/kg
Remarks on result:
other: Estimate from Log Kow
Validity criteria fulfilled:
not applicable
Conclusions:
The estimated KOC based on the KOW data equals 0.2218 L/kg. The calculated KOC from the molecular connectivity index is 1L/kg.
Executive summary:

Both estimated soil organic carbon-water partitioning coefficients indicate that the substance does not inherent a high tendency to adsorb on to soil particles, but is more likely to be found in aquatic compartments. The estimated KOC based on the KOW data equals 0.2218 L/kg. The calculated KOC from the molecular connectivity index is 1 L/kg.

This information is used in a read-across approach in the assessment of the target substance. For details and justification of read-across please refer to the read-across report attached to IUCLID section 13.

Description of key information

Both estimated soil organic carbon-water partitioning coefficients for the read across substance L(+)-lactic acid indicate that the substance does not inherent a high tendency to adsorb on to soil particles, but is more likely to be found in aquatic compartments. The estimated KOC based on the KOW data equals 0.2218 L/kg. The calculated KOC from the molecular connectivity index is 1L/kg. These QSAR calculations are supported by an experimental study, indicating that the KOC of lactic acid is much lower than 20.9.

Key value for chemical safety assessment

Koc at 20 °C:
1

Additional information