Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Study was given a Klimish score 4 according to OECD SIDS document (2002) for sodium hydroxide on following basis: original reference not available

Data source

Reference
Reference Type:
other:
Title:
No title available
Author:
Sax
Year:
1984
Bibliographic source:
cited in: Martin FM, Report EPA/600/8-88/081 Order-No. PB88-231949, 1988

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
not specified
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Name of test material (as cited in study report): sodium hydroxide

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
intraperitoneal
Vehicle:
not specified
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
40 mg/kg bw

Applicant's summary and conclusion