Registration Dossier
Registration Dossier
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EC number: 278-077-7 | CAS number: 75128-73-3
Eye irritation
Administrative data
- Endpoint:
- eye irritation
- Remarks:
- other: QSAR using Derek Nexus, version 2.0.0
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Study period:
- 2012
- Reliability:
- 2 (reliable with restrictions)
- Justification for type of information:
- QSAR prediction: migrated from IUCLID 5.6
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 012
- Report date:
- 2012
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Software used: DEREK Nexus, version 2.0.0, 2010 LHASA Ltd, Leeds, UK
- GLP compliance:
- no
Test material
- Reference substance name:
- 2-[(2-acetamido-6,9-dihydro-6-oxo-1H-purin-9-yl]methoxy]ethyl acetate
- EC Number:
- 278-077-7
- EC Name:
- 2-[(2-acetamido-6,9-dihydro-6-oxo-1H-purin-9-yl]methoxy]ethyl acetate
- Cas Number:
- 75128-73-3
- Molecular formula:
- C12H15N5O5
- IUPAC Name:
- 2-[(2-acetamido-6,9-dihydro-6-oxo-1H-purin-9-yl]methoxy]ethyl acetate
Constituent 1
Results and discussion
In vivo
Results
- Irritation parameter:
- other: prediction
- Remarks on result:
- other: No alert predicted.
Applicant's summary and conclusion
- Interpretation of results:
- other: no alert
- Remarks:
- Criteria used for interpretation of results: expert judgment
- Conclusions:
- No alert for ocular toxicity of the substance 2-[(2-acetamido-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]ethyl acetate was detected by DEREK Nexus version 2.0.0.
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