Registration Dossier

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Scientifically acceptable publication

Data source

Reference
Reference Type:
publication
Title:
Toxicity of lithium to humans and the environment - A literature review
Author:
Hal Aral, Angelica Vecchio-Sandus
Year:
2008
Bibliographic source:
Ecotoxicology and Environmental Safety 70: 349-356

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
A guideline for the toxicity testing has not been given since the publication deals with a literature review where specific data of toxicity testing with aquatic invertebrates has been collected and summarized.
GLP compliance:
not specified

Test material

Constituent 1
Reference substance name:
Li2SO4
IUPAC Name:
Li2SO4
Details on test material:
- Name of test substance (as cited in publication): lithium sulfate

Sampling and analysis

Analytical monitoring:
not specified

Test organisms

Test organisms (species):
Daphnia magna

Study design

Water media type:
freshwater
Total exposure duration:
24 h

Results and discussion

Effect concentrations
Duration:
24 h
Dose descriptor:
EC50
Effect conc.:
33 mg/L
Nominal / measured:
nominal
Conc. based on:
element
Remarks:
Lithium
Basis for effect:
mobility
Remarks on result:
other: equivalent to 244 mg/L Li3PO4
Details on results:
Conversion:
33 mg/L : 6.94 u (atomic weight of Li) = 4.7 mol Li
4.7 mol : 2 x 103.01 (molecular weight of Li2SO4) = 244 mg/L

Applicant's summary and conclusion