Registration Dossier

Administrative data

Endpoint:
toxicity to other aquatic vertebrates
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: see 'Remark'
Remarks:
The presented data have been retrieved from US EPA's ECOTOX Database, Version 4 (2012). This database provides single chemical toxicity information for aquatic and terrestrial life. The concomitant information within the database (such as indentification of guidelines and methods used) is reduced to the necessary minimum and usually not reported. Nevertheless, the toxicity data deposited has been derived from peer-reviewed literature and can therefore be regarded as valid information.

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Analysis of Physiological and Toxicological Effects of Potassium on Dreissena polymorpha and Toxicological Effects on Fish.
Author:
Durand-Hoffman, M.E.
Year:
1995
Bibliographic source:
M.S. Thesis, Ohio State University, Columbus, OH:90
Reference Type:
secondary source
Title:
ECOTOX: Aquatic Report
Author:
U.S. EPA
Year:
2012
Bibliographic source:
ECOTOX Database Version 4.0

Materials and methods

Principles of method if other than guideline:
A test guideline is not available.
GLP compliance:
not specified

Test material

Constituent 1
Reference substance name:
Lithium chloride
EC Number:
231-212-3
EC Name:
Lithium chloride
Cas Number:
7447-41-8
IUPAC Name:
lithium chloride

Sampling and analysis

Analytical monitoring:
no

Test organisms

Test organisms (species):
other: Dreissena polymorpha

Study design

Test type:
static
Water media type:
freshwater
Total exposure duration:
24 h

Test conditions

pH:
6.5 - 8.5

Results and discussion

Effect concentrations
Duration:
24 h
Dose descriptor:
LC50
Effect conc.:
185 mg/L
Nominal / measured:
nominal
Conc. based on:
element
Remarks:
Lithium
Basis for effect:
mortality
Remarks on result:
other: equivalent to 1031 mg/L Li3PO4
Details on results:
Conversion:
185 mg/L : 6.94 u (atomic weight of Li) = 26.7 mmol/L
26.7 mmol/L : 3 = 8.9
8.9 x 115.82 (molecular weight of Li3PO4) = 1031 mg/L

Applicant's summary and conclusion