Registration Dossier

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Description of key information

Key value taken from study report on Daphnia Magna

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
95 mg/L

Additional information

As the substance is a gas, the volatility of the substance precludes aquatic exposure.  Regulation (EC) No 2037/2000 of the European Parliament and of the Council of 29 June 2000 on substances that deplete the ozone layer lists within ANNEX I states that the substance is listed as a Group 1 substance. However, the registrant has a derogation in accordance with Regulation (EC) No 1005/2009 of the European Parliament and of the Council of 16 September 2009 on substances that deplete the ozone layer that allows for use of the substance as a processing agent. 

In accordance with the above two pieces of legislation, release is strictly controlled. As such, no release to the aquatic environment is envisaged. However, the registrant is able to present twovalues as follows:


K2 Study: 48 EC50: 95 mg/l

QSAR assessment: 48 EC50: 38.909 mg/l


These values are largely equivalent, thus detailing the validity of the QSAR model utilised.


On the basis of this, it is proposed that the substance could potentially be hazardous to Daphnia.


The risk phrase: H412: Harmful to aquatic life with long lasting effects is applicable.