Registration Dossier
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Diss Factsheets
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EC number: 200-893-9 | CAS number: 75-71-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Adsorption / desorption
Administrative data
Link to relevant study record(s)
Description of key information
Value calculated by QSAR, based on physical form and no release.
Key value for chemical safety assessment
- Koc at 20 °C:
- 74.86
Additional information
CFC-12 is not considered to show significant adsorption on the basis of this data.
No information was found pertaining to the adsorption of dichlorodifluoromethane onto soils and sediments. Given the physical form of the substance (gaseous) and the fact that it is a “CFC” and hence release is prohibited in accordance with Regulation (EC) No 2037/2000 on substances that deplete the ozone layer, significant exposure to soil is not anticipated. As such, it is deemed appropriate to assess the potential for soil adsorption utilising a QSAR technique. US EPA On-Line EPI Suite™ model KOCWIN Program (v2.00) for the estimation of soil adsorption coefficent (Koc) of organic compounds was chosen, as the substance is included in the data set for this model, and is known to be of sufficient accuracy. A QPRF detailing this justification is appended within the study summary. The substance was found to have an estimated Koc value of 43.89 L/kg (MCI Estimate) and 74.86 L/Kg (Log Kow estimate). The value from the Log Kow value is taken as the definitive value, as CFC-12 itself is an “Experimental Database Structure Match” andis used as a reference source in KOWWIN v 1.68, which is used to derive calculations of log Kow as part of the programme. On the basis of the results, the substanceis not proposed to adsorb/desorb strongly within soil. This estimate fits with the physical form of the substance.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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