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Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Acceptable publication; no details on purity of the test material.

Data source

Reference
Reference Type:
publication
Title:
Range-Finding Toxicity Data: List VII
Author:
Smyth HF, Carpenter CP, Weil CS, Pozzani UC, Striegel, JA and Nycum JS
Year:
1969
Bibliographic source:
American Industrial Hygiene Association Journal, Vol. 30, No. 5: 470-476

Materials and methods

Principles of method if other than guideline:
Method: no data given
GLP compliance:
no
Remarks:
; GLP was not compulsory at the time the study was conducted.
Test type:
other: no data given

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Name of test material (as cited in study report): Calcium hydroxide
- Analytical purity: no data given

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
oral: gavage
Vehicle:
water
Details on oral exposure:
Concentration intubated was 100 mg/ml
Doses:
no data given
No. of animals per sex per dose:
no data given
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
7 340 mg/kg bw

Applicant's summary and conclusion