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Ecotoxicological information

Toxicity to birds

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Administrative data

Endpoint:
short-term toxicity to birds: acute oral toxicity test
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Referenceopen allclose all

Reference Type:
review article or handbook
Title:
DPIM: FFY000
Author:
Richard J. Lewis, Sr.
Year:
2007
Bibliographic source:
SAX (Sax's Handbook of Dangerous Industrial Materials):- Toxicology and Applied Pharmacology. 21 (1972), 315.
Reference Type:
review article or handbook
Title:
RTECS Number: BY1575000
Year:
2012
Bibliographic source:
RTECS (Registry of Toxic Effects of Chemical Substances):- Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 21,315,1972
Reference Type:
review article or handbook
Title:
DOSE No.: F60
Author:
RSC Publishing
Year:
2011
Bibliographic source:
Dictionary of Substances and their effects (DOSE):- Schafer, E. W. Toxicol. Appl. Pharmacol. 1972, 21, 315-330.
Reference Type:
other: Authoritative data base
Title:
GCID: 221820
Year:
2011
Bibliographic source:
ACToR (Aggregated Computational Toxicology Resource):- Toxicology and Applied Pharmacology. Vol. 21, Pg. 315, 1972.

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other:
Principles of method if other than guideline:
Data is taken from SAX, DOSE, RTECS and ACToR Database
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Name of test material: 4-fluoroaniline
- Molecular formula: C6H6FN
- Molecular weight: 111.12
- Substance type: Organic
- Physical state: Liquid
Dose method:
other: peroral
Analytical monitoring:
not specified
Vehicle:
not specified

Test organisms

Test organisms (species):
other: Redwing blackbird

Study design

Remarks:
Exposure duration not reported
No. of animals per sex per dose and/or stage:
no data
Control animals:
not specified

Results and discussion

Effect levels
Dose descriptor:
other: LD50
Effect level:
100 mg/kg bw
Conc. / dose based on:
test mat.
Basis for effect:
mortality
Remarks on result:
other: Exposure duration not reported
Repellency factors (if applicable):
Details of toxic effects not reported other than lethal dose value

Applicant's summary and conclusion

Conclusions:
Oral toxicity (LD50) of 4-fluoroaniline to Redwing blackbird was examined at dose concentration of 100 mg/kg of body weight.
Executive summary:

The acute oral toxicity of 369 chemicals was determined for 1 or more species of wild birds, always including either red-winged blackbirds or starlings. Of these, 180 chemicals were toxic to 1 or more species at 100 mg/kg or less. Statistical comparison of redwing, starling and rat data indicated that redwings were more sensitive to chemicals than starlings, and both were more sensitive than rats.

Oral toxicity (LD50) of 4-fluoroaniline to Redwing blackbird was examined at dose concentration of 100 mg/kg of body weight.