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Diss Factsheets

Physical & Chemical properties

Water solubility

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
23rd December 1994 to 31st March 1995
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Remarks:
Study conducted in compliance with agreed protocols, with no or minor deviations from standard test guidelines and/or minor methodological deficiencies, which do not affect the quality of relevant results.
Reason / purpose for cross-reference:
reference to other study
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Remarks:
Date of inspection: 31st January 1994 Date of signature: 16th March 1994
Type of method:
flask method
Specific details on test material used for the study:
Container: metal canister
Storage conditions: Room temperature until 1st December 1994, thereafter room temperature in the dark.
Key result
Water solubility:
1.28 g/L
Incubation duration:
25 - 73 h
Temp.:
20 °C
pH:
6.8 - 7.1

Individual results:

 Equilibration time at 30°C (hours) Concentration (g/L)  pH
 251/2  1.26  7.1
 491/2  1.31  6.9
 731/2  1.27   6.8

Repeatability is less than 15%; therefore results are considered constant (i.e. equilibrium reached), and the retained value is the mean of the three individual results.

Conclusions:
Interpretation of results (migrated information): soluble (1000-10000 mg/L)
The water solubility of ST 02 C 94 was determined to be 1.28 g/L of solution at a temperature of 20.0°C and pH 7.
Executive summary:

Method: The experimental procedure used complied with that specified in EU Method A6, flask method.

Comments: The absorbance of the pair of standards associated with a particular sample were corrected to nominal concentration and the mean value taken prior to the calculation of the sample concentration.

Results: The water solubility of ST 02 C 94 was determined to be 1.28 g/L of solution at a temperature of 20 +/- 0.5°C and pH 6.8 -7.1.

Description of key information

Experimental water solubility at 20°C and pH 7.
Considered as soluble, with equilibrium reached from =< 24h.

Key value for chemical safety assessment

Water solubility:
1.28 g/L
at the temperature of:
20 °C

Additional information

An experimental study on water solubility measurement of the test material, was conducted under GLP, and considered as fully reliable. Therefore the result is considered as key data.