Registration Dossier
Registration Dossier
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EC number: 213-935-6 | CAS number: 1067-55-6
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The following study has been submitted to address the short-term toxicity to aquatic invertebrates endpoint:
Steger-Hartmann T and Wendt B (1998). AAcute immobilization test of di-n-butyltin oxide (ZK 26385) with Daphnia magna. Testing laboratory: Schering AG, Experimentelle Toxikologie, D-13342 Berlin, Germany. Report no.: IC26. Owner company: Schering AG, Experimentelle Toxikologie, Berlin Germany. Study number: TXST19980203. Report date: 1998-12-03.
The study has been allocated a Klimisch score of 2 and is the key study for this endpoint. The data presented is on the substance dibutyltin oxide.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 2 mg/L
Additional information
An EC50 (48 h) of 2 mg/l and a NOEC of 1.1 mg/l was recorded for acute toxicity to aquatic invertebrates
Read-across from dibutyltin oxide to dibutyl dimethoxystannane concerning aquatic toxicity endpoints was considered appropriate as dibutyltin and octyltins are known to hydrolyse rapidly in water (as presented by Yoder 2003, under the data requirement hydrolysis), and form, in the case of dibutyltins, dibutyltin oxide.
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