Registration Dossier

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

The following study has been submitted to address the short-term toxicity to aquatic invertebrates endpoint:
Steger-Hartmann T and Wendt B (1998). AAcute immobilization test of di-n-butyltin oxide (ZK 26385) with Daphnia magna. Testing laboratory: Schering AG, Experimentelle Toxikologie, D-13342 Berlin, Germany. Report no.: IC26. Owner company: Schering AG, Experimentelle Toxikologie, Berlin Germany. Study number: TXST19980203. Report date: 1998-12-03.
The study has been allocated a Klimisch score of 2 and is the key study for this endpoint. The data presented is on the substance dibutyltin oxide.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
2 mg/L

Additional information

An EC50 (48 h) of 2 mg/l and a NOEC of 1.1 mg/l was recorded for acute toxicity to aquatic invertebrates

Read-across from dibutyltin oxide to dibutyl dimethoxystannane concerning aquatic toxicity endpoints was considered appropriate as dibutyltin and octyltins are known to hydrolyse rapidly in water (as presented by Yoder 2003, under the data requirement hydrolysis), and form, in the case of dibutyltins, dibutyltin oxide.