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Ecotoxicological information

Short-term toxicity to fish

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Link to relevant study record(s)

Description of key information

The following information is available for the short-term acute toxicity to fish endpoint:
Steger-Hartmann T. & Wendt B. (1998) Acute toxicity of di-n-butyltin oxide (ZK 26385) to the Zebra fish Danio rerio. Testing laboratory: Schering AG, Experimentelle Toxikologie. Report no.: IC19. Owner company: Schering AG Report date: 1998-12-11.
The Steger-Hartmann and Wendt study, as a stand alone study it is a relaibility 1, however as it is used for read-across purposes, the study has been assigned a reliability 2 (reliable with restrictions). The data presented is on the substance dibutyltin oxide.

Key value for chemical safety assessment

Additional information

From the Steger-Hartmann T. & Wendt B. (1998) study, a LOEC of 3.1 mg/L was determined.

Read-across from dibutyltin oxide to dibutyl dimethoxystannane concerning aquatic toxicity endpoints was considered appropriate as dibutyltin and octyltins are known to hydrolyse rapidly in water (as presented by Yoder 2003, under the data requirement hydrolysis), and form, in the case of dibutyltins, dibutyltin oxide.

Due to the similarity between these the test substance and registration substance, it is considered justified to read across to this study.