Registration Dossier
Registration Dossier
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EC number: 249-323-0 | CAS number: 28950-61-0
Endpoint summary
Administrative data
Description of key information
The substance has a low potential for bioaccumulation (logKow < 3) and a low potential to cross biological membranes (high molecular weight, high polarity); furthermore, direct and indirect exposure of the aquatic compartment is unsuitable.
Nevertheless, bioaccumulation studies are available on the analogous substance of the category of Stilbene Fluorescent Whitening Agents, CAS 16090-02-1 and are here reported for completeness sake and in order to have a better overview of the PBT assessment.
In all the experiments performed only sporadic trace concentrations (less than 0.05 mg/kg) of the substance were present in the fish at exposure levels up to of 1 mg/l. In most instances, no detectable substance was found. The substance CAS 16090-02-1 is the analogous substance morpholino derivative, disodium salt. This substance is much less soluble than CAS 41098-56-0 (1.9 g/l versus 201 g/l) and the morpholino group make it potentially more reactive (enzymatic opening of morpholino ring on N atom), therefore it can be considered a conservative representative for CAS 41098-56-0 regarding bioaccumulation potential. Furthermore, the Bioconcentration Factor (BCF) value was calculated using BCFBAF v3.01 tool, an application contained in the EpiSuite 4.1[1]. The estimation takes into account the substance is a ionic compound. The BCF estimated value from regression-based method is 0.5 (BCF = 3.175 l/kg wet-wt), in agreement with the common value of non bioaccumulative substances.
[1]EpiSuite is the suite of physical/chemical property and environmental fate estimation programs developed by the EPA’s Office of Pollution Prevention Toxics and Syracuse Research Corporation (SRC).
Additional information
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