Registration Dossier
Registration Dossier
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EC number: 203-810-4 | CAS number: 110-87-2
Endpoint summary
Administrative data
Description of key information
Skin: The test substance was shown to be irritating to the skin of rabbits.
Eye: In a study with rabbits eye irritation was detected.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Additional information
Skin irritation:
The undiluted test substance was droped at a test patch (2.5 x 2.5 cm). After adsorption the patch was placed on the upper third of the back or flanks. The untreated skin sites served as the negative control. The reading of the parameter was conducted 24, 48, 72 hours, and 8 days after removal of the test patches. Based on the results of the available data, the test substance showed irritative effects after application to the skin of rabbits. [BASF, 1982]
Eye irritation:
On the basis of the findings, the test substance must be described as moderately irritating to the eyes. When the test substance acts on the eyes, corneal opacity must be expected. The pathological findings on the eye and the signs of irritation to the eye substantially subsided within 8 days. [BASF, 1978]
Justification for classification or non-classification
Based on the results obtained in skin irritation study with rabbits, the test substance has to be classified with respect to skin irritation, cat. 2, H315 "Causes skin irritation" according to Regulation (EC) No 1272/2008 (CLP, GHS).
Based on the results obtained in an eye irritation study with rabbits the test substance has to be classified with respect to eye irritation, cat. 2, H319 "Causes serious eye irritation" according to Regulation (EC) No 1272/2008 (CLP, GHS).
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