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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

oral: The acute oral LD50 was investigated in a study with rats and was determined to be 4264 mg/kg bw.
inhal.: The acute LC50 was determined to be greater than 10.7 mg/kg bw in rats.

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Dose descriptor:
LD50
Value:
4 264 mg/kg bw

Additional information

oral:

After a single oral dose administered to rats the calculated LD50 value of 3,4 -Dihydropyrane was 4264 mg/kg bw. [BASF, 1978]

inhal.:

The acute toxicity after inhalation was investigated in a study performed with rats. Rats were exposed to air enriched with 3,4 -Dihydropyrane for 4 hours in a whole body inhalation chamber. Based on the available data, the test substance needs not to be classified since no mortality was observed. [BASF, 1978]

Justification for classification or non-classification

Classification for acute oral, dermal and inhalation toxicity is not warranted according to the criteria of EU Classification, Labelling and Packaging of Substances and Mixtures (CLP) Regulation (EC) No 1272/2008.